Hs crp is raised in musculoskeletal inflammation also. Does is diverts our prognosis in ACS
Dr. Akshata SwamyBeginner
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C-reactive protein is produced by the body when blood-vessel walls are inflamed.
its marker of inflammation.
now understand that inflammation is of two types .1)acute inflammation and 2) chronic inflammation.
Acute inflammation is observed when there are some external factors like trauma responsible for it. ( like musculoskeletal injury )
but chronic inflammation occurs due to chronic APATHYA / diseases like DM , HTN, Addictions etc .
Now let me tell you the difference between CRP and HsCRP
C-reactive protein is measured down to concentrations of 3 to 5 mg/L, where as hs-CRP is measured down to concentrations of approximately 0.3 mg/L. This improved sensitivity allows hs-CRP to be used to detect low levels of chronic inflammation.
That means HsCRP gives you an understanding of chronic inflammation which is responsible for plaque formation and sometimes for Thrombus formation causing MI.
in such cases, Diet kit , panchakarma, exercise, and herbal RASAYAN dravyas can improve hscrp significantly so that risk of ACS can be reduced .
Thank you sir, fr detail explanation
To Diagnose an ACS, Cardiac specific markers like Troponin I, Troponin T can be more effective.
NT-ProBNP can be Further used for prognostic monitoring of Heart Failure.
Cardiac muscle functional damage post ACS, can be assessed by a 2D Echo Cardiography. GLS can help in prognosis of Ischemic Heart conditions.
CRP is a protein produced by liver in response to systemic inflammatory conditions like Viral Fevers, Rheumatoid arthritis, Bacterial infections etc. As prognostic parameters in musculoskeletal pain, it is better to use parameters like Range of motion, increase in mobility and reduction in subjective pain on Pain scales.
Yes thank u sir i get it , cardiac biomarkers pose risks of CVDs or to rule out ACS but hs-Crp plays exquisitely systemic marker of inflammation, predictor of future Cvds