Modafinil, including Modalert 200 can produce cardiac side effects, particularly in those who already have cardiovascular disease. For people with cardiac issues, arrhythmias, or hypertension, it may result in an elevated heart rate and blood pressure, which can be problematic. Although there are very few severe heart-related adverse effects, some users may have high blood pressure, palpitations, or chest discomfort. When used as directed, there is little danger for healthy people. To prevent any problems, Modalert 200 should always be used under a doctor’s supervision. Additionally, anyone with cardiac issues should speak with their doctor before taking it.